Skip to main content
. 2021 Jul 14;11(11):3508–3526. doi: 10.1016/j.apsb.2021.07.006

Figure 8.

Figure 8

Effects of Ampkα2−/−, Akt2−/−, and DKO on the levels of inflammatory cytokines, autophagy/mitophagy markers, and FoxO1 in livers from mice fed LF or HF diet. The protein levels of TNF-α (a), IL-6 (b), LC3BII (c), p62 (d), TOM20 (e), Parkin (f), FUNDC1 (g), BNIP3 (h), and FoxO1 (phosphorylated and pan-, pFoxO1-to-FoxO1 ratio, i) were examined using Western blot analysis. Representative gel blots which depicted the levels of TNF-α, IL-6, LC3BI/II, p62, TOM20, Parkin, FUNDC1, BNIP3, FoxO1, and phosphorylated FoxO1 were shown. Data are expressed as mean ± SEM (n = 6–9). ∗P < 0.05 vs. WT mice; #P < 0.05 vs. WT-HF mice; †P < 0.05 vs. DKO-HF mice.