Table 4:
Continuity and Progression of Externalizing Diagnoses from Baseline to Month 48 and From Month 48 to Month 96
| Baseline diagnosis | Month 48 diagnosis | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ADHD-HI/C (n=104) | ODD (n=89) | CD (n=26) | SUD (n=5) | |||||||||
| OR | 95% CI | p | OR | 95% CI | p | OR | 95% CI | p | OR | 95% CI | p | |
| ADHD-HI/C (n=350) | - | - | - | 1.12 | 0.68–1.82 | .659 | 1.39 | 0.56–3.47 | .481 | N/A | N/A | N/A |
| ODD (n=241) | 1.32 | 0.82–2.13 | .260 | - | - | - | 1.46 | 0.48–4.43 | .505 | N/A | N/A | N/A |
| CD (n=52) | 2.40 | 1.08–5.34 | .032 | 3.22 | 1.35–7.70 | .009 | - | - | - | N/A | N/A | N/A |
| SUD (n=0) | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | - | - | - |
| Month 48 diagnosis | Month 96 diagnosis | |||||||||||
| ADHD-HI/C (n=58) | ODD (n=47) | CD (n=17) | SUD (n=24) | |||||||||
| OR | 95% CI | p | OR | 95% CI | p | OR | 95% CI | p | OR | 95% CI | p | |
| ADHD-HI/C (n=104) | - | - | - | 2.69 | 1.33–5.44 | .006 | 1.15 | 0.37–3.61 | .805 | 0.52 | 0.15–1.82 | .304 |
| ODD (n=89) | 0.97 | 0.44–2.12 | .935 | - | - | - | 5.24 | 1.61–17.12 | .006 | 1.70 | 0.61–4.74 | .314 |
| CD (n=26) | 2.89 | 0.95–8.78 | .061 | 10.08 | 3.55–28.63 | <.001 | - | - | - | 3.78 | 1.08–13.28 | .038 |
| SUD (n=5) | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | - | - | - |
Note. All diagnoses derived from the Kiddie Schedule for Affective Disorders and Schizophrenia (see text for details). N/A indicates no diagnoses or no comorbid associations to predict later diagnoses. ADHD-HI/C=attention-deficit/hyperactivity disorder hyperactive-impulsive/combined subtypes; ADHD-IN=ADHD inattentive subtype; CD=conduct disorder; ODD=oppositional defiant disorder; OR=odds ratio. SUD=substance use disorder;