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. 2021 Nov 11;12(4):607–615. doi: 10.1016/j.jaim.2021.06.005

Table 2.

Cisplatin protective protocol.

Parameter
(Male)
Vehicle
(0.3%CMC)
Cisplatin
(5 mg/kg)
TK
(500 mg/Kg)
TK
(1000 mg/Kg)
Creatinine (mg/dL) 0.83 ± 0.02 1.183 ± 0.16∗ 0.81 ± 0.01 0.80 ± 0.0
BUN (mg/dL) 14.02 ± 0.6452 23.02 ± 1.644∗∗ 20.12 ± 2.53 15.17 ± 0.716
Uric Acid (mg/dL) 1.75 ± 0.10 1.76 ± 0.12 1.35 ± 0.06∗ 1.48 ± 0.06
Sodium (mmol/L) 120.7 ± 0.84 118.7 ± 1.11 116.0 ± 1.29 119.0 ± 1.50
Potassium (mmol/L) 13.82 ± 0.46 15.02 ± 0.44 15.55 ± 0.30 15.67 ± 0.75
Chloride (mmol/L) 106.7 ± 0.33 108.2 ± 0.47 108.3 ± 0.55 108.2 ± 0.47
Calcium (mmol/L) 1.73 ± 0.02 1.73 ± 0.02 1.85 ± 0.02 1.917 ± 0.122
Total Protein (g/dL) 7.08 ± 0.03 6.91 ± 0.18 7.06 ± 0.03 6.93 ± 0.05

Values presented as mean ± SEM; n = 06; One-way ANOVA; ∗ = p < 0.05 vs. control ∗∗ = p < 0.01 vs. control,  = p < 0.05 vs. Cisplatin control.