Table 1.
Demographic, laboratory, and CT-derived body composition characteristics of prefrail and frail patients stratified by gender. Baseline characteristics labeled with * represent trauma cohort data only (n = 102, 47.2%; prefrail women n = 21, frail women n = 51; prefrail men = 9, frail men = 21)
| Characteristic | Female | P value | Male | p value | ||
|---|---|---|---|---|---|---|
| Baseline characteristics (n, median (IQR)) | Prefrail (N = 37) | Frail (N = 114) | Prefrail (N = 14) | Frail (N = 51) | ||
| Age, y | 78.0 (71.5–83.5) | 84.0 (76.0–89.0) | 0.004 | 76.0 (72.8–82.0) | 82.0 (77.0–88.0) | 0.03 |
| Race (white) (n, %) | 27 (75.0) | 78 (76.0) | 1.0 | 13 (92.8) | 36(78.3) | 0.43 |
| Less than 60 days between geriatric evaluation and CT imaging (n, %) | 26 (70.3) | 76 (66.7) | 0.84 | 11 (78.6) | 36 (70.6) | 0.80 |
| Injury severity score* | 13.0 (8.5–18.0) | 13.0(9.0–17.0) | 0.70 | 8.0 (4.5–19.5) | 10.0 (4.0–17.0) | 0.79 |
| Total hospital days* | 5.0 (3.0–6.5) | 5.0 (4.0–7.0) | 0.48 | 6.0 (5.5–8.0) | 7.0 (3.5–10.0) | 0.82 |
| Total ICU days* | 2.0 (0.0–3.5) | 3.0 (0.0–4.0) | 0.31 | 1.0 (0–3.0) | 3.0 (0–6.0) | 0.35 |
| Charlson comorbidity index (CCI)* | 4.0 (3.0–5.5) | 6.0 (5.0–7.0) | 0.001 | 5.0 (3.5–6.5) | 6.0 (4.5–7.0) | 0.26 |
| Discharge to home (n, %)* | 4 (19.0) | 3 (5.9) | 0.18 | 1 (11.1) | 0 (0.0) | 0.30 |
| Albumin (mg/dL) | 4.0 (3.2–4.3) | 3.7(3.2–4.2) | 0.15 | 4.1 (3.4–4.2) | 3.7 (3.0–4.2) | 0.34 |
| BMI | 25.8 (22.7–28.4) | 23.9(20.7–27.8) | 0.18 | 27.1 (25.5–27.9) | 24.0 (21.5–26.4) | 0.01 |
| Proportion of obese or underweight patients based on BMI (n, %) | 7 (18.9) | 36 (31.6) | 0.2 | 2 (14.2%) | 10 (19.6%) | 0.83 |
| CT-derived body composition characteristics | ||||||
| L3 vertebra attenuation (HU) | 99.0 (76.0–127.0) | 75.0 (48.5–121.3) | 0.03 | 122.5 (92.5–140.3) | 97.0 (67.0–137.0) | 0.15 |
| Skeletal muscle index (SMI), cm/m2 | 41.6 (35.2–45.5) | 37.0 (32.3–42.8) | 0.06 | 47.1 (42.9–51.4) | 42.3 (38.1–49.5) | 0.07 |
| Visceral adipose tissue (VAT), cm2 | 118.6 (56.5–152.1) | 91.4 (52.6–172.9) | 0.58 | 192.7 (133.1–302.8) | 155.9 (74.3–280.4) | 0.35 |
| Subcutaneous adipose tissue (SAT), cm2 | 205.0 (160.9–264.8) | 203.7 (129.3–302.3) | 0.63 | 188.8 (133.0–221.5) | 137.1 (102.7–175.9) | 0.01 |
| Visceral obesity ratio (VOR) | 0.49 (0.27–0.73) | 0.51 (0.33–0.66) | 0.85 | 0.97 (0.70–1.60) | 1.22 (0.74–1.77) | 0.54 |