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. Author manuscript; available in PMC: 2021 Dec 4.
Published in final edited form as: Eur Respir J. 2021 Jul 29;58(1):2003434. doi: 10.1183/13993003.03434-2020

Figure 5: Diversity correlations with SCFA measurements:

Figure 5:

(A) Levels of SCFAs with Acetate, Propionate, Isovalerate and Butyrate were tested (PERMANOVA) against Beta Diversity distribution of data from all three sequencing techniques in BAL samples. Relative abundance of three KOs with direct annotation to measured SCFAs were compared across sample types: K01738 (Acetate), K00925 (Propionate) and K01034 (Butyrate) with (B) 16S rRNA gene sequencing, (C) Whole Genome Sequencing and (D) RNA metatranscriptome sequencing. (E) RNA metatranscriptome taxonomic annotation for these three SCFAs-associated KOs in UA, BAL.RNA.SPT, BAL.RNA.BPT and BKG samples are represented here. Each circle represents a different sample type and colors indicate a different taxonomic annotation.