Table 5.

Therapy Protocols

Protocol	Detail	With Complete Information
O-W-F-W fixed periodic treatment plan	The median outcome of screened plans compared with the outcome of the standard of care, and the plan with median stability compared with the optimal plan.	No
O-F-W fixed periodic treatment plan	The median outcome of screened plans compared with the outcome of the standard of care.	No
Standard of care	Conventional sequential treatment, that is, when tumor volume exceeds the initial volume during the continuous osimertinib administration, switch to FK866 and osimertinib combination administration.	No
Optimal plan	The optimal plan was calculated by simulated annealing.	Yes