. Author manuscript; available in PMC: 2023 Feb 1.

Published in final edited form as: J Am Acad Child Adolesc Psychiatry. 2021 Jun 5;61(2):308–320. doi: 10.1016/j.jaac.2021.04.014

Table 3.

Subcortical Volume Differences in Healthy Controls (n=64) versus Adolescents Diagnosed with Depressive and/or Anxiety Disorders (n=129)

	B	t(182)	p	d	% Diff.
Thalamus	−0.10	−0.78	.44	−0.12	0.96%
Caudate	−0.14	−0.83	.40	−0.13	1.60%
Putamen	−0.19	−1.20	.23	−0.20	2.34%
Pallidum	−0.22	−1.51	.13	−0.24	2.27%
Hippocampus	−0.16	−1.09	.28	−0.18	1.57%
Amygdala	−0.29	−2.04	.04	−0.33	3.39%
Nucleus accumbens	−0.51	−3.20	.001 ^*	−0.51	8.32%

Note. Results indicate group difference effects from regression models controlling for intracranial volume, age, sex, IQ, pubertal status, handedness, ADHD, medication, and head motion during the T1. B values represent standardized regression coefficients. Negative B, t-statistic, and d values indicate smaller subcortical volumes among adolescents diagnosed with depressive and/or anxiety disorders vs. healthy participants. The % Diff column indicates the percent difference between groups in estimated marginal means of volume. Volumes represent averages across left and right hemispheres. Boldface type indicates significant effects.

FDR-corrected p-value<.05.