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. 2021 Oct 14;224(11):1821–1829. doi: 10.1093/infdis/jiab509

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Figure 3. — Culture positivity and duration of symptoms. A, Viral load for each specimen was determined by quantitative polymerase chain reaction and plotted against the duration of symptoms (in days). Analysis by Pearson correlation. B, Viral load reported by binned duration of symptoms. Ordinary 1-way analysis of variance (ANOVA) used for analysis. C, Duration of symptoms for samples with observable cytopathic effect (CPE) (culture positive [+], n = 29) and without observable CPE (culture negative [-], n = 85). Analysis by t test. D, Semiquantitative viral titer reported by binned duration of symptoms, analyzed by ordinary 1-way ANOVA. Dotted lines depict limit of detection. ∗∗P < .01, ∗∗∗∗P < .0001.