Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Nov 20;224(11):1861–1872. doi: 10.1093/infdis/jiab535

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2021. Published by Oxford University Press for the Infectious Diseases Society of America.

This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence (https://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited. For commercial re-use, please contact journals.permissions@oup.com

PMC Copyright notice

Figure 4. — ASCs in lymphoid tissues and blood. A, SARS-CoV-2 spike protein (S1+S2)-specific IgM (blue) and IgG (red) ASCs were quantified in the spleen (n=4) at 3 and 21 dpi using an ELISPOT assay. Circles represent individual data obtained from each macaque and bars represent mean±SEM (unpaired Student t test; ∗P<.05, ∗∗∗∗P<.0001). B, The ASCs were enumerated in peripheral blood mononuclear cells (n=4) at the indicated dpi (1-way analysis of variance with Dunnett test for multiple comparisons vs 0 dpi; ∗P<.05, ∗∗∗P<.001). Abbreviations: ASC, antibody-secreting cell; dpi, days postinfection; ELISPOT, enzyme-linked immunospot; Ig, immunoglobulin; SARS-CoV-2, severe acute respiratory syndrome coronavirus 2; SEM, standard error of the mean.