Table 2.
Summary of membrane feeding experiments and infectivity by age group
| Age group, in y, n | |||||
|---|---|---|---|---|---|
| 2–5 (n=7) | >5–15 (n=40) | >15 (n=21) | All ages (n=68) | p | |
| Asexual parasite density per μL, median (IQR) | 1120 (400–9520) | 4480 (1200– 145 600) | 1440 (0–4160) | 3040 (480–8960) | 0.096b |
| Gametocyte density per μL, median (IQR) | 128 (40–208) | 120 (32–256) | 32 (16–224) | 80 (28–244) | 0.537b |
| Fever (≥37.5°C), % | 57.1 (4/7) | 37.5 (15/40) | 42.9 (9/21) | 41.1 (28/68) | 0.106c |
| Infectious individuals, % | 57.1 (4/7) | 62.5 (25/40) | 42.9 (9/21) | 55.9 (38/68) | 0.147c |
| Infected mosquitoes, % | 8.2 (67/815) | 17.9 (804/4495) | 13.0 (307/2357) | 15.4 (1178/7667) | 0.170c |
| Infected mosquitoes, %a | 14.3 (67/470) | 29.0 (804/2774) | 30.2 (307/1016) | 27.7 (1178/4260) | 0.039*,c |
| Mean infection intensity (range) | 3.5 (1–18) | 9.1 (1–475) | 2.3 (1–25) | 4.9 (1–475) | 0.317b |
| Dissected mosquitoes per feed, median (IQR) | 120 (111.5–130.5) | 112 (109–118.5) | 114 (108–118) | 114 (109–120) | 0.860c |
aMedian, only data from infectious individuals included; bKruskal–Wallis test to assess between-group difference; cχ2 test to assess between group difference.
*p<0.05.