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. 2021 Nov 10;49(21):12106–12118. doi: 10.1093/nar/gkab1041

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© The Author(s) 2021. Published by Oxford University Press on behalf of Nucleic Acids Research.

This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (https://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com

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Figure 1. — The immunology regulons across cancer types. (A) Number of samples across 33 cancer types. The red and blue numbers imply the number of cancer and normal samples, separately. (B) Immune-related pathways with different colors used in this study. (C) Overview of four type regulons identified by extended ImmLnc across cancer types. The top panel showing the number of regulons enriched in immune pathways across cancers. The middle panel showing the distribution of the number of regulons enriched in each immune pathway across cancer (log2 transformed). The bottom panel showing the proportion of regulons enriched in each immune pathway across cancers.