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. 2021 Nov 12;49(21):12136–12151. doi: 10.1093/nar/gkab1044

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© The Author(s) 2021. Published by Oxford University Press on behalf of Nucleic Acids Research.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 7. — Model of epigenetic regulation of nuclear lamina-associated heterochromatin domains by HAT1 and the acetylation of newly synthesized histones. (A) Schematic diagram showing the potential role of HAT1 and the acetylation of newly synthesized histones in the epigenetic inheritance of histone H3 methylation in heterochromatin. (B) Schematic diagram describing the regulation of nuclear lamina-heterochromatin interactions following DNA replication by nascent chromatin maturation.