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. 2021 Nov 25;49(21):12422–12432. doi: 10.1093/nar/gkab1077

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© The Author(s) 2021. Published by Oxford University Press on behalf of Nucleic Acids Research.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 2. — Secondary structure prediction of representative mitochondrial pre-rRNA group II introns newly identified in dimorphic fungi. Important tertiary interactions used as folding constraints (EBS1-IBS1, EBS2-IBS2, α-α’ and γ-γ’) are indicated in the secondary structure diagrams. (A–C) The mitochondrial large subunit rRNA introns in Histoplasma capsulatum (H.c.LSU.I1), Blastomyces dermatitidis (B.d.LSU.I2) and Coccidioides immitis (C.i.LSU.I3), respectively. (D) The mitochondrial small subunit rRNA intron found in Coccidioides immitis (C.i.SSU.I1). The intronic domain 4 of B.d.LSU.I2, C.i.LSU.I3 and C.i.SSU.I1 introns, are reduced to a simple stem-loop capped with UUCG tetraloop.