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Comparison by GelCompar of AluI restriction digests representing all pattern types defined for the 11 vaccine serotypes. Normalized band patterns are represented on the right, and a dendrogram of relatedness of patterns by use of the Dice coefficient is on the left. Pattern matches of 100% (tolerance, 1.0 + 1.75%) are demonstrated between the 4/5A patterns produced by isolates of serotypes 4 and 5 and the 18c/19fA patterns from the 18C and 19F isolates.
