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. 2021 Jun 21;187(4):1916–1928. doi: 10.1093/plphys/kiab298

Table 1.

Arabidopsis orthologs of yeast and mammalian TA protein insertion pathways

GET pathway
Yeast/mammalian	AGI Code	Gene name^a	Protein localization	References
GET1/WRB	At4g16444	AtGET1	ER membrane^b	Srivastava et al., 2017; Xing et al., 2017
GET2/CAML	At4g32680	AtGET2	ER membrane^b	Asseck et al., 2021
GET3/TRC40	At1g01910	AtGET3^a	Cytosol^b	Srivastava et al., 2017; Xing et al., 2017
	At3g10350	AtGET3^b	Chloroplast stroma^b
	At5g60730	AtGET3^c	Mitochondria matrix^b
GET4/TRC35	At5g63220	AtGET4	Cytosol^b	Srivastava et al., 2017; Xing et al., 2017
GET5/UBL4A	At1g55060	UBQ12	Cytosol^c	Srivastava et al., 2017
SGT2/SGTA	At4g08320	TPR8	Nucleus^c	Srivastava et al., 2017
BAG6	At2g46240	BAG6	Nucleus^c	PSI-BLAST, TAIR

SND pathway

SND1	Not found	–	–	PSI-BLAST
SND2	At4g30500At2g23940	AtSND2^a	Plasma membrane^c	PSI-BLAST
SND2	At4g30500At2g23940	AtSND2^b	ER membrane^c	PSI-BLAST
SND3	Not found	–	–	PSI-BLAST

ER Membrane Complex (EMC)

EMC1	At5g11560	PNET5	ER membrane^c	PSI-BLAST, TAIR
EMC2	At3g04830	AtEMC2^a	ER membrane^c	PSI-BLAST, TAIR
EMC2	At5g28220	AtEMC2^b	Cytosol^c	PSI-BLAST, TAIR
EMC3	At4g12590	AtEMC3	ER membrane^c	PSI-BLAST, TAIR
EMC4	At5g10780	AtEMC4	ER membrane^c	PSI-BLAST, TAIR
EMC5	At5g03345	PRCE2	ER membrane^c	PSI-BLAST, TAIR
EMC6	At5g49540	AtEMC6	Plasma membrane^c	PSI-BLAST, TAIR
EMC7	At2g25310	AtEMC7^a	ER membrane^c	PSI-BLAST, TAIR
EMC7	At4g32130	AtEMC7^b	ER membrane^c	PSI-BLAST, TAIR
EMC8/9	At5g55940	EMB2731	ER membrane^c	PSI-BLAST, TAIR
EMC10	Not found	–	–	PSI-BLAST

^a

Found annotated at TAIR (Arabidopsis.org) or—if designated as unknown protein—our suggestion for future use.

^b

Experimentally validated, see referenced publication for details.

^c

Predicted using SUBA (suba.live).

PSI, Position-specific iterative