Table 4.
Patient-reported IBD-DI, EQ-5D and WPAI scores in the PPIE population by ARM
| ARM 1 | ARM 2 | Overall | |
|---|---|---|---|
| EQ-5D total score (n) | 994 | 637 | 1631 |
| Mean (SD) | 0.81 (0.17) | 0.86 (0.16) | 0.83 (0.17) |
| Median (IQR) | 0.84 (0.21) | 0.90 (0.19) | 0.86 (0.18) |
| EQ-5D VAS score (n) | 1001 | 647 | 1648 |
| Mean (SD) | 71.2 (18.3) | 76.6 (16.2) | 73.3 (17.7) |
| Median (IQR) | 75 (25) | 80 (20) | 75 (25.5) |
| IBD-DI score (n) | 1000 | 647 | 1647 |
| Mean (SD) | 30.6 (18.9) | 22.3 (16.6) | 27.3 (18.5) |
| IBD control score, UK only (n) | 29 | 42 | 71 |
| Mean (SD) | 7.1 (3.7) | 7.3 (2.1) | 7.2 (2.9) |
| WPAI Scores in Total PPIE population | 1001 | 647 | 1648 |
| Work time missed (absenteeism; %) | 517 (52) | 324 (50) | 841 (51) |
| Mean (SD) | 0.11 (0.25) | 0.06 (0.19) | 0.09 (0.23) |
| Impairment (presenteeism; n) | 484 (48) | 315 (49) | 799 (48) |
| Mean (SD) | 0.24 (0.21) | 0.18 (0.19) | 0.22 (0.20) |
| Work productivity loss (n) | 484 (48) | 315 (49) | 799 (48) |
| Mean (SD) | 0.28 (0.24) | 0.20 (0.21) | 0.25 (0.23) |
| Activity Impairment (n) | 602 (60) | 368 (57) | 970 (59) |
| Mean (SD) | 0.27 (0.24) | 0.18 (0.20) | 0.24 (0.23) |
EQ-5D EuroQol-5 dimension, IBD-DI inflammatory bowel disease disability index, IQR interquartile range, n number, PPIE patient and public involvement and engagement, SD standard deviation, UK United Kingdom, VAS visual analogue scale, WPAI work productivity and activity impairment