Table 2.

Relationship between oncological outcomes and 2-year local recurrence-free rates.

Oncological outcomes		2-year LR over total	2-year LRFR (%)	HR	95% CI	p value
Tumor type	Myxofibrosarcoma	7/33	79
Gender	Male	4/17	76	2.33	0.24–22.44	0.46
	Female	1/12	92
Age	≤60 years old	1/11	91	0.50	0.05–4.80	0.55
	>60 years old	4/18	78
Tumor size	≤10 cm	7/20	65	N/A∗∗	44–86%∗∗	0.02∗∗
	>10 cm	0/13	100
Margin size	Negative ≤0.1 cm	3/8	63	7.97	0.83–76.79	0.07
	Negative >0.1 cm	1/18	94
Surgical margins	Positive	3/7	57	—	—	—
	Close margins∗	3/8	63	0.95	0.19–4.73	0.95
	Negative >0.1 cm	1/18	94	0.11	0.01–1.07	0.06
Grouped surgical margins	Positive or close∗	6/13	54	11.74	1.41–97.74	0.02
	Negative >0.1 cm	1/20	95
Tumor depth	Subcutaneous	5/17	71	2.56	0.50–13.21	0.26
	Intramuscular	2/16	88
Tumor character	Well-circumscribed	2/18	89	0.30	0.06–1.54	0.15
	Infiltrative	5/15	67
Re-resection intraoperatively†	Re-resection done	2/4	50	N/A∗∗	1–99%	0.19∗∗
	Re-resection not done	0/3	0
Re-resection postoperativelyˆ	Re-resection done	0/4	100	N/A∗∗	100%∗∗	0.07∗∗
	Re-resection not done	2/3	67%
Adjuvant therapy	Chemotherapy and radiotherapy	0/17	100%	N/A∗∗	100%∗∗	0.001∗∗
	Chemotherapy alone	3/4	25%
	Radiotherapy alone	2/8	75%
	No treatment	2/4	50%

Note. LRFR = 2-year local recurrence-free rate; LR = local recurrence; HR = hazard ratio; CI = confidence interval. ^∗Close margins = negative margins ≤0.1 cm; ^∗∗the Kaplan–Meier log-ranked test was used to assess statistical significance; †re-resections were done intraoperatively due to positive intraoperative pathology report; ˆre-resections were done postopearatively due to positive final pathology report.