Table 5.

Univariate and multivariate analyses of overall survival in PAAD patients of the ICGC cohort.

Variables	Univariate analysis			Multivariate analysis
	Hazard ratio	95% CI	P value	Hazard ratio	95% CI	P value
Gender (male vs. female)	1.268	0.944–1.702	0.114
Age (>65 vs. ≤65)	0.562	0.39–0.81	0.002∗	0.295	0.102–0.857	0.025∗
T stage (T3 + T4 vs. T1 + T2)	0.779	0.545–1.112	0.169
N stage (N1 + Nx vs. N0)	0.796	0.61–1.038	0.092
M stage (M1 + Mx vs. M0)	0.985	0.744–1.305	0.981
TNM stage (stage III + IV vs. stage I + II)	0.917	0.642–1.310	0.633
CIMP status
CIMP-M vs. CIMP-L	1.016	0.717–1.439	0.929
CIMP-H vs. CIMP-L	2.01	1.274–3.193	0.003∗	1.849	1.146–2.984	0.012∗