Table 2.
Results of neuroimaging analysis.
| Modality | Region | MNI Coordinates |
Statistic |
Cluster Size | |
|---|---|---|---|---|---|
| x/y/z | T-value | p-value (FWE) | |||
| FDOPA-PET t-test (FOG+<FOG-) | CAU_L | −8/8/10 | 3.84 | 0.008 | 112 |
| rs-fMRI CAUL (FOG+>FOG-) |
CAL_R Occi_Sup_R |
20/-88/4 | 5.38 | 0.033 | 70 |
| rs-fMRI VTAbil (FOG+>FOG-) |
Parietal_inf_L Occi_Mid_L AG_L |
−36/-74/40 | 5.71 | < 0.001 | 447 |
| AG_R Occi_Mid_R |
48/-72/36 | 4.91 | < 0.001 | 237 | |
| SFG_R | 22/30/46 | 5.21 | < 0.001 | 134 | |
| PCUN_L CAL_L |
−14/-58/16 | 4.84 | 0.014 | 74 | |
| PCUN_R CAL_R |
16/-44/4 | 4.69 | 0.012 | 76 | |
Neuroimaging results by modality and contrast. T-values were calculated using SPM12. Rs-fMRI analyses were conducted in Conn. The bilateral VTA (AALv3) was used as seed region for FDOPA-PET MC. Seed regions for seed-based correlation analysis were CAU_L and bilateral VTA (VTAbil). Abbreviations: AG_L: angular gyrus left, AG_R: angular gyrus right, CAL: calcarine sulcus, CAU_L: left caudate nucleus, Occi_Mid_L: mid occipital cortex left, Occi_Mid_R: mid occipital cortex right, Occi_Sup_R: superior occipital cortex right, Parietal_Inf_L: inferior parietal cortex left, PCUN: precuneus, SFG_R: right superior frontal gyrus.