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. 2021 Nov 22;12:769699. doi: 10.3389/fgene.2021.769699

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Copyright © 2021 Deng, Xu, Chen, Guo, Steiner, Chen, Cheng, Xu, Yao, Li, Wang, Deng, Schrodi, Zhang and Xin.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Ezetimibe Corrected the Phenotypes of the Proband. Panel (A) shows the changes in the LDL-C levels under an optimized treatment regimen. Panel (B) shows the disappearance of the aforementioned atherosclerotic plaque revealed by the ultrasound scan after Ezetimibe treatment. Panel (C) shows the comparison of platelet size distributions before and after Ezetimibe treatment in the proband. Panel (D) shows the disappearance of the large platelet in the blood smear of the proband after treatment of Ezetimibe.