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. 2021 Nov 22;11:725926. doi: 10.3389/fonc.2021.725926

Table 2.

The performance of all models in predicting GAE in the training and testing cohorts.

Model Cohort AUC (95% CI) Accuracy Sensitivity Specificity PPV NPV
Clinical model Training 0.762 (0.667–0.846) 0.748 0.721 0.780 0.800 0.696
Testing 0.799 (0.672–0.917) 0.782 0.750 0.815 0.808 0.759
Radiomics features-combined model Training 0.879 (0.805–0.939) 0.811 0.770 0.86 0.870 0.754
Testing 0.724 (0.575–0.855) 0.673 0.536 0.815 0.750 0.629
Clinical–radiomics model Training 0.886 (0.819–0.940) 0.820 0.803 0.840 0.860 0.778
Testing 0.836 (0.7070.937) 0.782 0.750 0.815 0.808 0.759

In the process of establishing scout models to select features, only the cross-validation performance was assessed to avoid information leakage. The bold values is optimal value.

AUC, area under the curve; PPV, positive predictive value; NPV, negative predictive value.