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. 2021 Nov 25;19:6343–6354. doi: 10.1016/j.csbj.2021.11.033

Fig. 3.

Fig. 3

DNA damage response genes that are responsible for the pathogenicity of C. albicans cells. Typical genes involved in different DDR pathways are selected. RAD52, LIG4, RTT109, RFX2, RAD23 and TOP2 play positive roles in pathogenicity. TOP1, PPH3, PSY2 and PSY4 play negative roles in pathogenicity. SDS22 overexpression attenuates pathogenicity.