Table 2.
Isolate number | MLST | Intrinsic blaOXA gene | Antimicrobial resistance genes | Efflux pumps genes | QRDRb | ||||
---|---|---|---|---|---|---|---|---|---|
Pasteur | Oxford | gyrA | parC | ||||||
ST | CC | ST | CC | ||||||
M02 | 85 | 464 | 1089 | 1078 | bla OXA-94 | aph(3′)-VI, blaNDM-1, blaADC (disrupted by IS6), mphE, msrE, sul2, ant(2″)-Ia, ant(3″)-IIc | adeABC, adeIJK, adeFGH, abeM, amvA, abeS, abaF, abaQ, floR, macAB | S83L | S80L |
M11 | 85 | 464 | 1089 | 1078 | bla OXA-94 | aph(3′)-VI, blaNDM-1, blaADC (disrupted by IS6), mphE, msrE, sul2, ant(2″)-Ia, ant(3″)-IIc | adeABC, adeIJK, adeFGH, abeM, amvA, abeS, abaF, abaQ, floR, macAB | S83L | S80L |
M19 | 164 | 164 | 1418 | 234 | bla OXA-91 | aph(3′)-VI, blaNDM-1, blaADC-257a, blaCARB-16, ant(2″)-Ia, ant(3″)-IIc | adeABC, adeIJK, adeFGH, abeM, amvA, abeS, abaF, abaQ, macAB | S83L | S80L |
M20 | 570 | 2 | 1701 | 546 | bla OXA-66 | blaOXA-23, aph(3′)-VI, blaNDM-1, blaADC-73, aph(3′)-Ia, blaTEM-1, aph(3″)-I, aac(6′)-Ib’, catB8, ant(3″)-Ia, sul1, ArmA, msr(E), mph(E), ant(3″)-IIc | adeABC, adeIJK, adeFGH, abeM, amvA, abeS, abaF, abaQ, macAB | S83L | S80L |
Novel ADC allele.
QRDR, quinolone resistance determining regions.