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. 2021 Nov 18;42(6):692–709. doi: 10.24272/j.issn.2095-8137.2021.272

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Editorial Office of Zoological Research, Kunming Institute of Zoology, Chinese Academy of Sciences

This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Changes in expression of genes in virus-infected tree shrew tissues and cells

A: Changes in newly annotated genes upon viral infection. HBV, hepatitis B virus; NDV, Newcastle disease virus; EMCV, encephalomyocarditis virus; HSV-1, herpes simplex virus type 1; SeV Sendai virus; ZIKA, Zika virus. Genes were identified as differentially expressed genes (DEGs) upon virus infection if P_adjust<0.05 and |log2 fold-change|>1. B: Plot of DEGs upon virus infection.PURA and IFI35 were dysregulated in cells and tissues infected with different viruses. Horizontal bar on left represents number of DEGs in each RNA-seq dataset. Dots and lines represent subsets of DEGs. Vertical histogram represents number of DEGs in each subset. C: Changes in expression of 19 gene copies of STT3B gene family upon SeV infection. Results are mean±standard deviation (SD). ^*: P_adjust<0.05;^**: P_adjust<0.005;^***, P_adjust<0.0005.P_adjust values were calculated using DESeq2.