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. 2021 Dec 1;6(6):100312. doi: 10.1016/j.esmoop.2021.100312

Figure 3.

Figure 3

Receiver operating characteristic curve (ROC) for prediction of relevant toxicity to cabozantinib in mRCC patients.

A threshold of 617.7 ng/ml for Ctrough had a 63.3% sensitivity and a 65.3% specificity to detect relevant toxicity (i.e. G3-4 toxicities and G2 toxicities determining a dose reduction or a drug discontinuation).