Table 2.
Manual optimized planned and AI based test results. The bold values indicate a significant higher dose and the italic values indicate a significant lower dose compared to the optimized plans (p < 0,05, Wilcoxon signed rank test). All values are in Gy except for the External-PTV clinical goal, which is in cm3.
| ROI | n* | Clinical goals | Manual | Predicted | Mimicked |
|---|---|---|---|---|---|
| PTVp | 12 | D98% [Gy] ≥ 38.0 Gy | 38.2 ± 0.2 | 38.7 ± 0.2 | 38.2 ± 0.1 |
| 12 | D2% [Gy] ≤ 42.8 Gy | 41.5 ± 0.3 | 41.1 ± 0.1 | 41.2 ± 0.4 | |
| 12 | 39.6 Gy ≤ Dmean [Gy] ≤ 40.4 Gy | 40.1 ± 0.2 | 40.3 ± 0.1 | 40.0 ± 0.2** | |
| PTVn1n2 | 12 | D98% [Gy] ≥ 38.0 Gy | 38.3 ± 0.3 | 38.7 ± 0.2 | 38.4 ± 0.2 |
| 12 | D2% [Gy] ≤ 42.8 Gy | 41.4 ± 0.3 | 40.8 ± 0.1 | 40.8 ± 0.3 | |
| PTVn3n4 | 6 | D98% [Gy] ≥ 38.0 Gy | 38.3 ± 0.2 | 38.7 ± 0.1 | 38.3 ± 0.2 |
| 6 | D2% [Gy] ≤ 42.8 Gy | 41.6 ± 0.5 | 40.9 ± 0.0 | 40.8 ± 0.1 | |
| Heart | 12 | Dmean [Gy] ≤ 2.5 Gy | 1.3 ± 0.3 | 1.4 ± 0.3 | 1.3 ± 0.3 |
| Lungs | 12 | Dmean [Gy] ≤ 6.0 Gy | 4.3 ± 0.6 | 4.4 ± 0.5 | 4.7 ± 0.5 |
| External-PTV | 12 | V42.85Gy [cm3] ≤ 10.0 cm3 | 0.2 ± 0.5 | 0.9 ± 1.4 | 2.4 ± 5.8** |
*Number of patients included in the evaluation. **One patient in the test set did not fulfil this goal.