Table 4.
Subgroup Analysis of the Associations Between 90-Day All-Cause Mortality and the SIRIa
| No. of Patients | HR (95% CI) b | P for Interaction | |
|---|---|---|---|
| Age, years | 0.2759 | ||
| <70 | 1225 | 1.02 (1.01, 1.03) | |
| ≥71 | 1225 | 1.01 (1.00, 1.02) | |
| Gender | 0.8323 | ||
| Male | 1281 | 1.01 (1.01, 1.02) | |
| Female | 1169 | 1.01 (1.01, 1.02) | |
| Ethnicity | 0.7819 | ||
| White | 1840 | 1.01 (1.01, 1.02) | |
| Black | 189 | 1.00 (0.95, 1.06) | |
| Other | 421 | 1.02 (1.00, 1.03) | |
| MAP, mmHg | 0.4585 | ||
| <82 | 1222 | 1.01 (1.01, 1.02) | |
| ≥83 | 1222 | 1.02 (1.01, 1.04) | |
| Heart rate, beats/minute | 0.8849 | ||
| <78 | 1222 | 1.02 (1.01, 1.02) | |
| ≥79 | 1223 | 1.01 (1.00, 1.02) | |
| Respiratory rate, times/minute | 0.8322 | ||
| <18 | 1221 | 1.02 (1.01, 1.02) | |
| ≥18 | 1222 | 1.01 (1.00, 1.02) | |
| Congestive hearts failure | 0.2162 | ||
| Yes | 232 | 1.01 (0.98, 1.04) | |
| No | 2218 | 1.01 (1.01, 1.02) | |
| Atrial fibrillation | 0.2627 | ||
| Yes | 698 | 1.01 (1.00, 1.02) | |
| No | 1752 | 1.02 (1.01, 1.02) | |
| Liver disease | 0.7741 | ||
| Yes | 63 | 1.09 (1.05, 1.13) | |
| No | 2387 | 1.01 (1.01, 1.02) | |
| Coronary artery disease | 0.4418 | ||
| Yes | 444 | 1.01 (1.00, 1.02) | |
| No | 2006 | 1.02 (1.01, 1.02) | |
| Pneumonia | 0.1167 | ||
| Yes | 553 | 1.02 (1.01, 1.03) | |
| No | 1897 | 1.01 (1.01, 1.02) | |
| Anion gap, mmol/l | 0.0494 | ||
| ≤14 | 994 | 1.01 (1.01, 1.02) | |
| ≥15 | 1447 | 1.02 (1.00, 1.03) | |
| Glucose, mg/dl | 0.0952 | ||
| ≤133 | 1207 | 1.03 (1.02, 1.04) | |
| ≥134 | 1241 | 1.01 (1.00, 1.02) | |
| Serum urea nitrogen, mg/dl | 0.1809 | ||
| ≤18 | 1196 | 1.02 (1.01, 1.03) | |
| ≥19 | 1253 | 1.01 (1.00, 1.02) | |
| Potassium, mmol/l | 0.8999 | ||
| ≤3.9 | 1096 | 1.02 (1.01, 1.02) | |
| ≥4.0 | 1354 | 1.01 (1.01, 1.02) | |
| Sodium, mmol/l | 0.4633 | ||
| ≥138 | 1011 | 1.01 (1.01, 1.02) | |
| ≥139 | 1438 | 1.02 (1.01, 1.02) | |
| APTT, second | 0.8038 | ||
| ≤26.6 | 1193 | 1.02 (1.01, 1.03) | |
| >26.7 | 1217 | 1.01 (1.01, 1.02) | |
| INR | 0.0214 | ||
| ≤1.0 | 578 | 1.02 (0.99, 1.05) | |
| ≥1.1 | 1836 | 1.01 (1.01, 1.02) | |
| PT, second | 0.6098 | ||
| ≤13.1 | 1140 | 1.02 (1.00, 1.04) | |
| ≥13.2 | 1274 | 1.01 (1.01, 1.02) | |
| SAPSII | 0.3413 | ||
| ≤34 | 1154 | 1.05 (1.02, 1.08) | |
| ≥35 | 1296 | 1.01 (1.00, 1.01) | |
| APSIII | 0.1427 | ||
| ≤37 | 1189 | 1.03 (1.02, 1.05) | |
| ≥38 | 1261 | 1.01 (1.00, 1.01) |
Notes: Cox proportional hazards regression models were used to calculate hazard ratios (HR) with 95% confidence intervals (CI). aCox proportional hazards regression models were used to calculate hazard ratios (HR) with 95% confidence intervals (CI). bcovariates were adjusted for age, sex and ethnicity.