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. 2021 Nov 22;9:791892. doi: 10.3389/fcell.2021.791892

FIGURE 2.

FIGURE 2

Biological function of circRNAs. (A). CircRNAs can act as miRNA sponges to regulate the expression of downstream genes. (B). CircRNAs can bind to RNA binding protein and regulate parental gene expression. (C). Some circRNAs can be carried by exosomes and involved in the process of cell-cell communication. (D). CircRNAs can encode proteins based on IRES-driven and m6A-driven models. (E). CircRNAs can bind with proteins to establish circRNA-protein complexes and alter the functions of some proteins.