TABLE 1.
The proliferation-related circular RNAs in GBM.
| circRNAs | Expression | Mechanism | Biological function | Ref.PMID |
|---|---|---|---|---|
| hsa_circ_0008344 | Up | — | Promote cell proliferation, colony formation and inhibit cell apoptotic rate | 29687495 |
| circ-MMP9 | Up | miR-124/CDK4 | Promote cell proliferation | 30470262 |
| hsa_circ_0029426 | Up | miR-197 | Promote cell proliferation and inhibit cell apoptosis | 30548670 |
| hsa_circ_0074027 | Up | miR-518a-5p/IL17RD | Promote cell proliferation, colony formation and inhibit cell apoptotic rate | 30738578 |
| hsa_circ_0067934 | Up | PI3K-AKT | Promote cell proliferation | 31081099 |
| circ-PITX1 | Up | miR-379–5p/MAP3K2 | Promote cell proliferation and inhibit cell apoptosis | 31493405 |
| circ-FOXO3 | Up | miR-138-5p/miR-432-5p/NFAT5 | Promote cell proliferation | 31504797 |
| hsa_circ_0001801 | Up | miR-628-5p/HMGB3 | Promote cell proliferation | 31858556 |
| circ-EPB41L5 | Up | miR-19a/EPB41L5 | Promote cell proliferation and colony formation | 31905344 |
| circ-ENTPD7 | Up | miR-101-3p/ROS1 | Promote cell proliferation | 32308563 |
| hsa_circ_0043278 | Up | miR-638/HOXA9 | Promote cell proliferation | 33154193 |
| circ-SMO | Up | SMO-193aa | Promote cell proliferation | 33446260 |
| circ-SKA3 | Up | miR-1 | Promote cell proliferation | 33500664 |
| circ-PARP4 | Up | miR-125a-5p | Promote cell proliferation | 33520365 |
| circ-PITX1 | Up | miR-584-5p/KPNB1 | Promote cell proliferation | 33763840 |
| circ-ABCC3 | Up | miR-770-5p/SOX2 | Promote cell proliferation and inhibit cell apoptosis | 33811842 |
| hsa_circ_0006168 | Up | miR-628-5p/IGF1R | Promote cell proliferation, colony formation and inhibit cell apoptotic rate | 34024251 |
| hsa_circ_0001588 | Up | miR-211-5p/YY1 | Promote cell proliferation | 34105224 |
| circ-FLN1 | Up | miR-199-3p | Promote cell proliferation | 34498720 |
| circ-SERPINE2 | Up | miR-361-3p/miR-324-5p/BCL2 | Promote cell proliferation, colony formation and inhibit cell apoptotic rate | 34553034 |
| — | — | — | ||
| circ-LGMN | Up | miR-127-3p/LGMN | Promote cell proliferation | 34582975 |
| circ-NF1 | Up | miR-340 | Promote cell proliferation | 34589042 |
| circ-NT5E | Down | miR-422a | Inhibit cell proliferation | 29967262 |
| hsa_circ_0001946 | Down | miR-671-5p/CDR1 | Inhibit cell proliferation and promote cell apoptosis | 30663767 |
| circ-MTO1 | Down | miR-92/WWOX | Inhibit cell proliferation | 31456594 |
| circ-AKT3 | Down | AKT3-174aa/PI3K/AKT | Inhibit cell proliferation | 31470874 |
| hsa_circ_01844 | Down | — | Inhibit cell proliferation and promote cell apoptosis | 32804726 |
| circ-CDR1as | Down | p53/MDM2 | Inhibit cell proliferation | 32894144 |