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. 2021 Nov 22;8:761978. doi: 10.3389/fnut.2021.761978

Table 1.

Demographic information and gastrointestinal discomfort symptoms in patients with psoriasis and common population.

Characteristic Total people Psoriasis patients Healthy controls P
N 326 159 167
Age, median (75% CI) years 37 (30–47) 36 (30–45) 37 (28–49) 0.301
Sex, n (%) 0.001
Male 192 (58.9) 108 (67.9) 84 (50.3)
Female 134 (41.1) 51 (32.1) 83 (49.7)
BMI, median (75% CI) 22.60 (20.68–25.36) 23.71 (21.22–26.45) 22.04 (20.31–24.09) <0.001
Disease duration, n (%)
<3 months 9 (5.7) NA
≥3, and <6 months 9 (5.7) NA
≥6, and <12 months 4 (2.5) NA
≥1, and <3 years 13 (8.2) NA
≥3, and <5 years 18 (11.3) NA
≥5 years 106 (66.6) NA
Severity of disease in the last 5 years, n (%)
Not affecting daily life at all 22 (13.8) NA
Slightly affecting daily life 95 (59.8) NA
Seriously affecting daily life 42 (26.4) NA
Disease involvement area in the last 5 years, n (%)
<1 palm 24 (15.1) NA
≥1 and <5 palms 32 (20.1) NA
≥5 and <10 palms 37 (23.3) NA
≥10 palms 66 (41.5) NA
Abdominal pain, n (%) <0.001
No 260 (79.8) 114 (71.7) 146 (87.4)
Slightly 60 (18.4) 39 (24.5) 21 (12.6)
Moderately 5 (1.5) 5 (3.2) 0 (0)
Seriously 1 (0.3) 1 (0.6) 0 (0)
Type of abdominal pain, n (%) 0.661
No 171 (52.5) 80 (50.3) 91 (54.5)
Colic pain 28 (8.6) 16 (10.1) 12 (7.2)
Dull pain 64 (19.6) 34 (21.4) 30 (17.9)
Stabbing pain 5 (1.5) 4 (2.5) 1 (0.6)
Cold pain 5 (1.5) 2 (1.3) 3 (1.8)
Gas pain 27 (8.3) 12 (7.5) 15 (9.0)
Others 26 (8.0) 11 (6.9) 15 (9.0)
Abdominal flatulence, n (%) <0.001
No 220 (67.5) 89 (56.0) 131 (78.4)
Slightly 96 (29.4) 61 (38.4) 35 (21.0)
Moderately 9 (2.8) 8 (5.0) 1 (0.6)
Seriously 1 (0.3) 1 (0.6) 0 (0)
Borborygmus, n (%) <0.001
No 265 (81.3) 115 (72.3) 150 (89.8)
Slightly 55 (16.9) 38 (23.9) 17 (10.2)
Moderately 4 (1.2) 4 (2.5) 0 (0)
Seriously 2 (0.6) 2 (1.3) 0 (0)
Gastric acid reflux, n (%) <0.001
No 238 (73.0) 92 (57.9) 146 (87.4)
Slightly 84 (25.8) 63 (39.6) 21 (12.6)
Moderately 3 (0.9) 3 (1.9) 0 (0)
Seriously 1 (0.3) 1 (0.6) 0 (0)
Back pain, n (%) <0.001
No 236 (72.4) 94 (59.1) 142 (85.0)
Slightly 80 (24.5) 59 (37.1) 21 (12.6)
Moderately 10 (3.1) 6 (3.8) 4 (2.4)
Seriously 0 (0) 0 (0) 0 (0)
Belching, n (%) <0.001
No 233 (71.5) 98 (61.7) 135 (80.8)
Slightly 91 (27.9) 59 (37.1) 32 (19.2)
Moderately 1 (0.3) 1 (0.6) 0 (0)
Seriously 1 (0.3) 1 (0.6) 0 (0)
Nausea or vomiting, n (%) <0.001
No 240 (73.6) 92 (57.8) 148 (88.6)
Slightly 77 (23.6) 58 (36.5) 19 (11.4)
Moderately 6 (1.9) 6 (3.8) 0 (0)
Seriously 3 (0.9) 3 (1.9) 0 (0)
Passing flatus, n (%) <0.001
No 227 (69.6) 87 (54.7) 140 (83.8)
Slightly 87 (26.7) 60 (37.7) 27 (16.2)
Moderately 10 (3.1) 10 (6.3) 0 (0)
Seriously 2 (0.6) 2 (1.3) 0 (0)
Urgency of defecation, n (%) <0.001
No 246 (75.5) 102 (64.1) 144 (86.2)
Slightly 63 (19.3) 41 (25.8) 22 (13.2)
Moderately 15 (4.6) 14 (8.8) 1 (0.6)
Seriously 2 (0.6) 2 (1.3) 0 (0)
Constipation, n (%) <0.001
No 216 (66.3) 78 (49.1) 138 (82.6)
Slightly 94 (28.8) 66 (41.5) 28 (16.8)
Moderately 15 (4.6) 14 (8.8) 1 (0.6)
Seriously 1 (0.3) 1 (0.3) 0 (0)
Stool frequency, n (%) 0.005
Once a day 205 (62.9) 90 (56.6) 115 (68.9)
2–3 times a day 65 (20.0) 36 (22.6) 29 (17.3)
More than 3 times a day 15 (4.6) 13 (8.2) 2 (1.2)
Once every 2–3 days 35 (10.7) 16 (10.1) 19 (11.4)
Once every 4–5 days 3 (0.9) 1 (0.6) 2 (1.2)
Once or less a week 3 (0.9) 3 (1.9) 0 (0)
Stool color, n (%) <0.001
Yellow brown 238 (73.0) 105 (66.1) 133 (79.6)
Green 8 (2.5) 7 (4.4) 1 (0.6)
Black 16 (4.9) 14 (8.8) 2 (1.2)
White 1 (0.3) 1 (0.6) 0 (0)
No attention 63 (19.3) 32 (20.1) 31 (18.6)
The characteristics of stool, n (%) <0.001
Soft and shaped 139 (42.6) 52 (32.7) 87 (52.1)
Thin strip 82 (25.2) 42 (26.4) 40 (23.9)
Liquid and shapeless 48 (14.7) 31 (19.5) 17 (10.2)
Dry and hard 12 (3.7) 11 (6.9) 1 (0.6)
Watery 0 (0) 0 (0) 0 (0)
Foamy 2 (0.6) 2 (1.3) 0 (0)
No attention 43 (13.2) 21 (13.2) 22 (13.2)

p-value were calculated by the Mann-Whitney U-test for age, BMI, and the chi-square test for other variables.

NA, not applicable.