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. 2021 Nov 22;12:730418. doi: 10.3389/fphys.2021.730418

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Copyright © 2021 Köller, Grzegorzewski, Tautenhahn and König.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Mapping of model cirrhosis degree on CTP-score. (A) Mapping based on ICG clearance (Figg et al., 1995; Møller et al., 1998). (B) Mapping based on ICG-kel (Herold et al., 2001; Møller et al., 2019). (C) Mapping based on ICG-R15 (Møller et al., 2019). (D) Mapping based on ICG-thalf (Møller et al., 2019). (E) Resulting f_cirrhosis values for each CTP-class combining the information from the mappings based on individual ICG pharmacokinetic parameters (Control: f_cirrhosis = 0.0; Mild cirrhosis: 0.41; Moderate cirrhosis: 0.70; Severe cirrhosis: 0.82).