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Pae restricted plaque formation and collagen deposition of aorta in ApoE-/- mice. (A) Scheme of the experiment. ApoE-/- mice were administered with Pae for 4 weeks starting at 12 weeks of HFD feeding. (B, C) H&E and Masson staining of aorta (scale bars, 100 μm). (D) α-SMA protein expression in the aorta by Western blot. Data are presented as mean ± SEM, n = 3. *p < 0.05, **p < 0.01.
