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. 2021 Nov 22;12:765482. doi: 10.3389/fphar.2021.765482

FIGURE 2.

FIGURE 2

Microbiota drive the antifibrosis effect in Pae-treated ApoE-/- mice. (A) The antifibrosis effect of Pae against HFD-induced AS disappeared after gut-microbiota depletion. (B) Pae microbial transplantation mitigated HFD-induced vascular fibrosis. Data are presented as mean ± SEM, n = 3. * p < 0.05, ** p < 0.01.