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. 2021 Nov 22;12:750516. doi: 10.3389/fphys.2021.750516

TABLE 1.

Demographics and sleep macrostructure of the participants.

N = 24
Age Years 55 (17)
Sex Female 29%
BMI kg/m2 33.8 (7.4)
Diagnostic AHI4% (N = 22) /h 41.2 (29.0)
Diagnostic AHI3A/RDI (N = 22) /h 55.8 (21.9)

CPAP OSASWS OSASWS + O2 p-value

Total sleep time (TST) h 6.6 (1.0) 6.6 (0.8) 7.1 ± 1.2 n.s.
Sleep efficiency (SE) % TST/TIB 88.0 (8.8) b 88.6 ± 8.4 92.6 (6.7) 0.04
Sleep onset latency (SOL) min 4.4 (5.2) 4.2 (5.8) 3.1 (7.0) n.s.
Wake after sleep onset (WASO) min 47.0 (41.9) 31.8 (50.3) 28.8 (36.2) n.s.
NREM 1 %TST 10.4 (4.3) 9.4 (4.9) 8.7 (5.8) n.s.
NREM 2 %TST 51.6 ± 7.1 54.1 ± 8.5 54.1 ± 6.4 n.s.
NREM 3 %TST 16.2 (5.9) a,b 13.8 (10.0) 13.1 (5.6) 0.01
REM %TST 21.4 ± 5.8 20.4 ± 5.9 21.9 ± 5.2 n.s.

AHI4%, apnea-hypopnea index (hypopnea 4% O2 desaturation criteria); AHI3A, apnea hypopnea index [hypopnea 3% O2 desaturation/electroencephalographic (EEG) arousal criteria]; TST, total sleep time; REM, rapid eye movement; NREM 1, non-REM stage 1; NREM 2, non-REM stage 2; SWS, slow-wave sleep.

aSignificant difference between continuous positive airway pressure (CPAP) and OSASWS conditions.

bSignificant difference between CPAP and OSASWS + O2 conditions; n.s., not significant. Values expressed as mean ± SD or median (interquartile range). All significance levels are for the Friedman or one-way repeated measures ANOVA tests.