Table 3.
Represents the Receptor-Ligand Interactions with selected ligands with Sucrose α-glucosidase (sucrase) and respective binding energies.
| Enzyme | Pdb Id | Pubchem Cid And Inhibitor Docked | Active Site Residues | Cdocker Energy (kcal/mol) | Residues Interactions |
|---|---|---|---|---|---|
|
Sucrose α-glucosidase Sucrose hydrolase (SUH) |
3CZE/3CZK | CID 44144284 Gymnemic Acid I |
PHE 140,PHE244 ARG278,ASP280 SER281,TYR284 GLU322,ILE324 VAL325, ASP392, HIS443, ARG515. |
-95.8172 | HIS443, GLU322, ALA323 |
| CID 10051937 Gymnemagenin |
-73.8771 | ILE324, VAL325, ASP392 | |||
| CID 14264063 Gymnemic acid IV |
-101.119 | ASP393, GLY395 | |||
| CID 91617592 Gymnemic Acid VII (NO interactions) |
NO interactions | GLU322, SER281, HIS443, PHE345, SER241, |