Table 5.
Association of total cholesterol burden with CMR morpho-functional parameters.
| Cholesterol burden, mg/dL-year | ||||
|---|---|---|---|---|
| Univariate |
Multivariatea |
|||
| β | p | β | p | |
| LV mass, g | 0·261 | 0·052 | 0·205 | 0·049 |
| LV Volume, mL | -0·218 | 0·107 | -0·241 | 0·067 |
| LV Mass to Volume, g/mL | 0·520 | < 0·001 | 0·493 | <0·001 |
| LV Ejection Fraction, % | 0·135 | 0·321 | 0·228 | 0·137 |
| LV myocardial tissue characterization | ||||
| Pre-contrast T1, ms | 0·032 | 0·817 | 0·141 | 0·346 |
| Post-contrast T1, ms | 0·094 | 0·492 | 0·015 | 0·915 |
| Partition coefficient (λ) | -0·075 | 0·584 | -0·035 | 0·830 |
| ECV, % | -0·134 | 0·325 | 0·037 | 0·802 |
| ERM, % | -0·081 | 0·554 | 0·019 | 0·888 |
| Presence of LGE, n | 0·000 | 0·117 | 0·000 | 0·350 |
BMI, Body mass index; ECV, extracellular volume; ERM, enhancement rate myocardium; LGE, late gadolinium enhancement; LV, Left Ventricle; SBP, systolic BP.
a
Adjusted for age, gender, BMI and SBP·