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. 2021 Sep 3;75(10):e14759. doi: 10.1111/ijcp.14759

TABLE 2.

Descriptive statistics for age, vital parameter, laboratory measurements and critically illness prediction scores of the groups

Mortality groups ICU requirement groups
Variable All patients (n = 481) Survivor (n = 361) Non‐survivor (n = 120) P IU (n = 396) ICU (n = 85) P
Age, median (25th‐75th)
Age 67 (52‐79) 63 (49‐76) 75 (66‐82) <.001 64 (50‐78) 75 (65.50‐81) <.001
Critically illness prediction scores, median (25th‐75th)
CURB‐65 (0‐5) 1.00 (0.00‐2.00) 1.00 (0.00‐2.00) 2.00 (2.00‐3.00) <.001 1.00 (0.00‐2.00) 3.00 (2.00‐3.00) <.001
ISARIC‐4C (0‐21) 8.00 (4.00‐11.00) 6.00 (3.00‐9.50) 13.00 (11.00‐15.75) <.001 7.00 (3.00‐10.00) 14.00 (11.50‐16.00) <.001
COVID‐GRAM (0‐100) 66.02 (30.11‐94.60) 47.2 (22.39‐80.99) 97.20 (84.05‐99.81) <.001 51.25 (24.29‐83.74) 98.39 (86.15‐99.94) <.001
Vital signs and GCS, median (25th‐75th)
SBP (mmHg) 120 (110‐138) 120 (110‐138) 120.5 (110‐137) .437 120 (110‐138) 126 (106‐139) .404
DBP (mmHg) 72 (66‐80) 73 (68‐80) 71 (65‐80) .114 71.5 (67‐80) 76 (63‐80) .672
HR (bpm) 87 (77‐98.50) 85 (75‐96) 95.50 (81‐106) <.001 85 (75‐96) 97 (85‐110) <.001
RR (bpm) 20 (16‐26) 18 (16‐22) 34 (24‐42) <.001 18 (16‐22) 40 (34‐44) <.001
Temp (℃) 36.70 (36.2‐37.2) 36.70 (36.20‐37.20) 36.70 (36.33‐37.40) .452 36.70 (36.20‐37.20) 37.00 (36.45‐37.45) .063
spO2 (%) 95 (90‐97) 96 (93‐98) 87 (81‐93.75) <.001 96 (93‐98) 85 (80‐87.50) <.001
GCS 15 (15‐15) 15 (15‐15) 15 (13.25‐15) <.001 15 (15‐15) 15 (13‐15) <.001
Laboratory measurements, median (25th‐75th)
WBC (103/μL) 6.50 (4.90‐9.35) 6.10 (4.70‐8.20) 8.45 (6.23‐12.83) <.001 6.20 (4.70‐8.30) 8.90 (6.45‐13.30) <.001
CRP (mg/L) 46.90 (14.3‐112.4) 30.5 (9.91‐86.55) 101 (57.1‐177.5) <.001 33.85 (11.53‐94.58) 106 (59.60‐181.0) <.001
Urea (mg/dL) 37 (27‐57) 33 (25‐46) 58 (38‐88) <.001 35 (26‐49.75) 58 (37‐89) <.001
LDH (U/L) 264 (193‐391) 256 (190‐356) 347 (220.3‐543.3) <.001 259 (190‐376.75) 364 (220.50‐567.50) <.001
D Bil. (μmol/L) 16.80 (11.49‐30.06) 14.14 (10.61‐23.87) 28.73 (16.80‐45.97) <.001 15.02 (10.61‐25.64) 30.06 (16.35‐51.71) <.001
NLR 4.50 (2.43‐8.57) 3.67 (2.13‐7.19) 8.13 (4.28‐13.72) <.001 3.85 (2.18‐7.41) 8.57 (5.72‐16.79) <.001

Abbreviations: CRP, c‐reactive protein; D Bil., direct bilirubin; DBP, diastolic blood pressure; GCS, Glasgow coma scale;HR, heart rate; ICU, intensive care unit; IU, inpatient unit; LDH, lactat dehydrogenase; NLR, neutrophile‐to‐lymphocyte ratio; P, asymptotic 2‐sided significance between groups with Mann Whitney U test; RR, respiratory rate; SBP, systolic blood pressure; spO2, blood oxygen saturation; Temp, body temperature; WBC, white blood cell.