TABLE 2.
Mortality groups | ICU requirement groups | ||||||
---|---|---|---|---|---|---|---|
Variable | All patients (n = 481) | Survivor (n = 361) | Non‐survivor (n = 120) | P | IU (n = 396) | ICU (n = 85) | P |
Age, median (25th‐75th) | |||||||
Age | 67 (52‐79) | 63 (49‐76) | 75 (66‐82) | <.001 | 64 (50‐78) | 75 (65.50‐81) | <.001 |
Critically illness prediction scores, median (25th‐75th) | |||||||
CURB‐65 (0‐5) | 1.00 (0.00‐2.00) | 1.00 (0.00‐2.00) | 2.00 (2.00‐3.00) | <.001 | 1.00 (0.00‐2.00) | 3.00 (2.00‐3.00) | <.001 |
ISARIC‐4C (0‐21) | 8.00 (4.00‐11.00) | 6.00 (3.00‐9.50) | 13.00 (11.00‐15.75) | <.001 | 7.00 (3.00‐10.00) | 14.00 (11.50‐16.00) | <.001 |
COVID‐GRAM (0‐100) | 66.02 (30.11‐94.60) | 47.2 (22.39‐80.99) | 97.20 (84.05‐99.81) | <.001 | 51.25 (24.29‐83.74) | 98.39 (86.15‐99.94) | <.001 |
Vital signs and GCS, median (25th‐75th) | |||||||
SBP (mmHg) | 120 (110‐138) | 120 (110‐138) | 120.5 (110‐137) | .437 | 120 (110‐138) | 126 (106‐139) | .404 |
DBP (mmHg) | 72 (66‐80) | 73 (68‐80) | 71 (65‐80) | .114 | 71.5 (67‐80) | 76 (63‐80) | .672 |
HR (bpm) | 87 (77‐98.50) | 85 (75‐96) | 95.50 (81‐106) | <.001 | 85 (75‐96) | 97 (85‐110) | <.001 |
RR (bpm) | 20 (16‐26) | 18 (16‐22) | 34 (24‐42) | <.001 | 18 (16‐22) | 40 (34‐44) | <.001 |
Temp (℃) | 36.70 (36.2‐37.2) | 36.70 (36.20‐37.20) | 36.70 (36.33‐37.40) | .452 | 36.70 (36.20‐37.20) | 37.00 (36.45‐37.45) | .063 |
spO2 (%) | 95 (90‐97) | 96 (93‐98) | 87 (81‐93.75) | <.001 | 96 (93‐98) | 85 (80‐87.50) | <.001 |
GCS | 15 (15‐15) | 15 (15‐15) | 15 (13.25‐15) | <.001 | 15 (15‐15) | 15 (13‐15) | <.001 |
Laboratory measurements, median (25th‐75th) | |||||||
WBC (103/μL) | 6.50 (4.90‐9.35) | 6.10 (4.70‐8.20) | 8.45 (6.23‐12.83) | <.001 | 6.20 (4.70‐8.30) | 8.90 (6.45‐13.30) | <.001 |
CRP (mg/L) | 46.90 (14.3‐112.4) | 30.5 (9.91‐86.55) | 101 (57.1‐177.5) | <.001 | 33.85 (11.53‐94.58) | 106 (59.60‐181.0) | <.001 |
Urea (mg/dL) | 37 (27‐57) | 33 (25‐46) | 58 (38‐88) | <.001 | 35 (26‐49.75) | 58 (37‐89) | <.001 |
LDH (U/L) | 264 (193‐391) | 256 (190‐356) | 347 (220.3‐543.3) | <.001 | 259 (190‐376.75) | 364 (220.50‐567.50) | <.001 |
D Bil. (μmol/L) | 16.80 (11.49‐30.06) | 14.14 (10.61‐23.87) | 28.73 (16.80‐45.97) | <.001 | 15.02 (10.61‐25.64) | 30.06 (16.35‐51.71) | <.001 |
NLR | 4.50 (2.43‐8.57) | 3.67 (2.13‐7.19) | 8.13 (4.28‐13.72) | <.001 | 3.85 (2.18‐7.41) | 8.57 (5.72‐16.79) | <.001 |
Abbreviations: CRP, c‐reactive protein; D Bil., direct bilirubin; DBP, diastolic blood pressure; GCS, Glasgow coma scale;HR, heart rate; ICU, intensive care unit; IU, inpatient unit; LDH, lactat dehydrogenase; NLR, neutrophile‐to‐lymphocyte ratio; P, asymptotic 2‐sided significance between groups with Mann Whitney U test; RR, respiratory rate; SBP, systolic blood pressure; spO2, blood oxygen saturation; Temp, body temperature; WBC, white blood cell.