TABLE 2.
Complications and outcomes
| Variable | Overall Cohort (N = 34 675) | Matched Cohort (N = 17 347) |
||
|---|---|---|---|---|
| Antiplatelet Treatment (N = 6781) | No Antiplatelet Treatment (N = 10 566) | p* | ||
| Thrombotic complications | ||||
| Thrombotic/embolic stroke | 176 (0.5) | 57 (0.8) | 72 (0.7) | .36 |
| PE | 876 (2.5) | 151 (2.2) | 321 (3.0) | .002 |
| STEMI | 114 (0.3) | 33 (0.5) | 38 (0.4) | .20 |
| Acute deep vein thrombosis | 874 (2.5) | 176 (2.6) | 289 (2.7) | .58 |
| Arterial thrombosis | 54 (0.2) | 15 (0.2) | 16 (0.2) | .29 |
| Hemorrhagic complications | ||||
| Cerebral hemorrhage | 122 (0.4) | 35 (0.5) | 43 (0.4) | .30 |
| Gastrointestinal hemorrhage | 822 (2.4) | 211 (3.1) | 283 (2.7) | .10 |
| Pulmonary hemorrhage | 176 (0.5) | 43 (0.6) | 56 (0.5) | .38 |
| Epistaxis | 169 (0.5) | 61 (0.9) | 46 (0.4) | <.001 |
| Blood transfusion | 1395 (4.0) | 187 (2.8) | 418 (4.0) | <.001 |
| Outcomes | ||||
| Hospital LOS, days | 8 (5–14) | 8 (5–15) | 8 (5–14) | <.001 |
| Mechanical ventilation | 10 633 (30.7) | 2122 (31.3) | 3403 (32.2) | .30 |
| In‐hospital mortality | 6510 (18.8) | 1280 (18.9) | 2271 (21.5) | <.001 |
Abbreviations: LOS, length of stay; PE, pulmonary embolism; STEMI, ST‐segment elevation myocardial infarction.
*Categorical variables are reported as number (percent). Continuous variables are represented as median (interquartile range). Chi‐squared test for categorical variables, Mann‐Whitney U test for continuous variables, pairwise comparison between antiplatelet therapy and non‐antiplatelet therapy groups.