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. 2021 Sep 8;14(1):e1754. doi: 10.1002/wnan.1754

TABLE 3.

Representative targets for diagnosing SARS‐CoV‐2

Target Type of test Function
ORF1ab gene Nucleic acid Encoding replicase polyprotein 1ab
ORF1b‐nsp14 gene Nucleic acid Encoding nonstructural protein 14
RdRP gene Nucleic acid Encoding RNA‐dependent RNA polymerase
S gene Nucleic acid Encoding spike glycoprotein (structural)
E gene Nucleic acid Encoding small envelope protein (structural)
M gene Nucleic acid Encoding matrix protein (structural)
N gene Nucleic acid Encoding nucleocapsid protein (structural)
Spike protein RBD domain Antibody Bind to ACE2 receptor

Abbreviations: ACE2, angiotensin‐converting enzyme 2; RBD, receptor binding domain.