TABLE 5.
Treatment | Test value | |||||||||
---|---|---|---|---|---|---|---|---|---|---|
Favipiravir1 | Favipiravir and Hydroxychloroquine2 | Hydroxychloroquine3 | P | |||||||
Median | 25 th percent | 75 th percent | Median | 25 th percent | 75 th percent | Median | 25 th percent | 75 th percent | ||
First neutrophil % | 62.15 | 54.80 | 70.20 | 63.75 | 57.35 | 71.20 | 57.50 | 49.00 | 68.20 | .179 |
First lymphocyte % | 26.55 | 17.50 | 33.30 | 23.25 | 16.75 | 31.95 | 26.35 | 19.30 | 34.90 | .487 |
First NLR | 2.45 | 1.69 | 3.65 | 3.02 | 1.91 | 3.80 | 2.24 | 1.57 | 3.58 | .286 |
First platelet | 224.00 | 191.00 | 283.00 | 221.50 | 182.00 | 255.00 | 250.00 | 212.00 | 290.00 | .066 |
First D‐dimer | 0.45 | 0.26 | 0.83 | 0.54 | 0.35 | 0.99 | 0.26 | 0.19 | 0.45 | <.001 |
First ferritin | 62.90 | 19.10 | 211.00 | 120.40 | 41.20 | 262.00 | 104.50 | 27.35 | 182.50 | .389 |
First CRP | 13.00 | 4.00 | 44.33 | 9.20 | 3.19 | 23.20 | 3.31 | 1.44 | 7.77 | <.001 |
After 1 month neutrophil % | 57.40 | 52.50 | 65.80 | 60.00 | 49.50 | 65.85 | 59.80 | 52.70 | 64.70 | .964 |
After 1 month lymphocyte % | 25.85 | 17.95 | 32.70 | 24.55 | 18.75 | 33.35 | 31.40 | 26.00 | 36.20 | .005 |
After 1 month NLR | 2.29 | 1.62 | 3.21 | 2.28 | 1.54 | 3.38 | 1.96 | 1.46 | 2.47 | .053 |
After 1 month platelet | 282.00 | 232.50 | 343.50 | 267.00 | 229.00 | 337.00 | 244.00 | 221.00 | 291.50 | .058 |
After 1 month D‐dimer | 0.42 | 0.30 | 0.80 | 0.46 | 0.31 | 0.68 | 0.30 | 0.19 | 0.55 | .014 |
After 1 month ferritin | 73.00 | 22.00 | 265.00 | 57.00 | 29.10 | 194.00 | 48.55 | 11.00 | 157.35 | .382 |
After 1 month CRP | 0.40 | 0.00 | 4.50 | 3.29 | 0.87 | 7.00 | 0.54 | 0.00 | 2.27 | <.001 |
Kruskal‐Wallis Test was used. First D‐dimer 1‐2:0.357 1‐3:<0.001 2‐3:<0.001, First CRP 1‐2:0.422 1‐3: <0.001 2‐3:0.058, After 1 mo D‐dimer 1‐2:1.000 1‐3:0.024 2‐3:0.033, After 1 mo CRP 1‐2:<0.001 1‐3:1.000 2‐3: <0.001.
Abbreviations: CRP, C‐reactive protein; NLR, neutrophil/lymphocyte ratio.