TABLE 1.

Cell death and CoVs

Autor	Ano	CoV	CellLine	Tissue	Cell death	Reference
Surjit, Milan et al.	2004	SARS‐CoV	COS‐1, HuH7	Kidney	Apoptosis	29
Tan, Yee‐Joo et al.	2004	SARS‐CoV	HEK293T, HeLa, A549, HepG2, Vero E6, COS‐7	Kidney, cervix, lung, liver,	Apoptosis	23
Ren, Lili et al.	2005	SARS‐CoV	Vero	Kidney	Apoptosis	70
Law, Patrick T W et al.	2005	SARS‐CoV	Vero E6	Kidney	Apoptosis	71
Kopecky‐Bromberg, Sarah A et al.	2006	SARS‐CoV	HEK293T, A549, and HeLa	Human embryonic kidney, lungs, cervix	Apoptosis	60
Khan, Sehaam et al.	2006	SARS‐CoV	Vero E6	Kidney	Apoptosis and neccrosis	52
Chan, Chak‐Ming et al.	2007	SARS‐CoV	HEK293T, TransgenicDrosophila	Kidney	Apoptosis	24
Chen, Chia‐Yen et al.	2007	SARS‐CoV	VeroE6, HEK 293T, and HuH‐7	Kidney human embryonic kidney	Apoptosis	52
Zhang, Lu et al.	2007	SARS‐CoV	COS‐1	Kidney	Apoptosis	75
Tan, Ying‐Xim et al.	2007	SARS‐CoV	VeroE6, HEK293T	Kidney	Apoptosis	62
Chan, E et al.	2008	SARS‐CoV	Vero E6 e 3a TransgenicDrosophilamodel	Kidney	Apoptosis	31
Padhan, Kartika et al.	2008	SARS‐CoV	Huh7	Kidney	Apoptosis	22
Ye, Zhongde et al.	2008	SARS‐CoV	Vero E6, COS‐7 cells and HEK293T cells	Kidney and human embryonic kidney	Apoptosis	58
Minakshi, Rinki et al.	2009	SARS‐CoV	COS‐1, Vero, Huh7	Kidney	Apoptosis	28
Freundt, Eric C et al.	2009	SARS‐CoV	Vero cells	Kidney	Apoptosis	73
Ye et al.	2010	SARS‐CoV	Vero E6 and COS‐7 cells	Kidney	Apoptosis	57
Sharma, Kulbhushan et al.	2011	SARS‐CoV	Vero cells	Kidney	Apoptosis	67
Tsoi, Ho et al.	2014	SARS‐CoV	HEK293FT	Kidney	Apoptosis	27
Nieto‐Torres, Jose L et al.	2014	SARS‐CoV	Vero E6, BHK‐21 cells	Kidney	Pyroptosis	110
Chu, Hin et al.	2016	MERS‐CoV	Peripheral blood mononuclear cells, Tcells and tonsil and spleen‐dissociated cells	Blood	Apoptosis	76
Yeung, Man‐lung et al.	2016	MERS‐CoV	Calu‐3 and normal human mesangial cells	Lungs, kidney	Apoptosis	79
Yue, Yuan et al.	2018	SARS‐CoV	HeLa, HEK 293T, A549, Thp‐1	Cervix, kidney, lung, peripheral blood	Necrosis	24
Chen, I‐Yin et al.	2019	SARS‐CoV	BMMs, HEK293FT, HeLa, HT‐1080	Kidney, Cervix, connective tissue	Pyroptosis	26
Shi, Chong‐Shan et al.	2019	SARS‐ CoV	THP‐1, HEK293, A549, HeLa	Peripheral blood, kidney, lung, cervix	Autophagy	32
Jiang, Yuting et al.	2019	MERS‐CoV	Human monocytic cells (THP‐1)	Blood	Pyroptosis	111
Carmona‐Gutierrez, Didac et al.	2020	MERS‐CoV,SARS‐CoV	‐	‐	Autophagy	54
Li, Shaohua et al.	2020	SARS‐CoV‐2	‐	‐	Pyroptosis	25
Li, Shufen et al.	2020	SARS‐CoV‐2	Calu‐3, Vero, Vero E6, THP‐1	Lung	ApoptosisNecroptosis	91
Shojaei, Shahla et al.	2020	SARS‐CoV‐2	‐	‐	Autophagy	53
Bellesi, Silvia et al.	2020	SARS‐CoV‐2	Peripheral blood T Lympocytes	Blood	Apoptosis	77
Ren, Yujie et al.	2020	SARS‐CoV‐2	VeroE6, HEK293T and HepG2	Kidney, lung	Apoptosis	72
Rodrigues, Tamara S et al.	2021	SARS‐CoV‐2	Peripheral blood mononuclear cells	Blood	Pyroptosis	112
Ferreira, André C et al.	2021	SARS‐CoV‐2	Vero E6, human primary monocytes	Kidney, blood	Pyroptosis	113

Abbreviations: CoVs, coronaviruses; MERS‐CoV, Middle East respiratory syndrome coronavirus; SARS‐CoV, severe acute respiratory syndrome coronavirus.