TABLE 1.

Main Characteristics of the studies included in the analyses

Author	Date	Stage of printing	Type of study	Location	Included positive cases (n)	Hospitalised patients (n)	Outpatients (n)	Age of total positive cases (Median/Mean [IQR/SD])
Argenziano, et al.	March 11th–April 6th	Print	Case series	US	1,000	850	150	63.0 [50.0–75.0]
Argyropoulos, et al.	March 12th–March 18th	Print	Retrospective cohort	US	205	40	165	NA
Avci, et al.	March 11th–April 21st	Print	Retrospective cohort	Turkey	1,197	215	982	NA
Baidal, et al.	March 1–May 14	Pre‐print	Retrospective cohort	US	8,055	5,136	2919	NA
Bermejo‐Martin, et al.	March 16th–April 15th	Print	Prospective cohort	Spain	250	200	50	NA
Blair, et al.	April 21st–June 23rd	Print	Prospective cohort	US	118	9	109	56.0 [50.0–63.0]
CDC COVID‐19 response team	February 12th–March 28th	Print	Report	US	6,637	1,494	5143	NR
Ebinger, et al.	March 8th–March 21st	Print	Retrospective cohort	US	442	214	228	52.7 [19.6]
Fan, et al.	February 28th–May 14th	Print	Cross‐sectional	US	88,747	27,062	61,685	NR
Giorgi Rossi, et al.	February 27th–April 2nd	Print	Prospective cohort	Italy	2,653	1,075	1578	NR
Gottlieb, et al.	March 4th–June 21st	Print	Retrospective cohort	US	8,673	1,483	7190	41.0 [29.0–54.0]
Gu, et al.	March 10th–April 22th	Print	Retrospective cohort	US	1,139	523	616	53.0 [39.0–66.0]
Hamer, et al.	March 16th–April 26th	Pre‐print	Prospective cohort	UK	387,109	760	386,349	57.1 [9.0]
Hao, et al.	March 4th–April 13th	Print	Cross‐sectional	US	2,566	929	1637	NA
Hernandez‐Galdamez, et al.	June	Print	Cross‐sectional	Mexico	211,003	65,495	145,508	45.7 [16.3]
Hsu, et al.	March 1st to May 18th	Print	Report	US	2,631	1,088	1543	NR
Izquierdo‐Dominguez, et al.	March 21st–April 18th	Print	Cross‐sectional	Spain	846	649	197	56.8 [15.7]
Jehi, et al.	March 8th to June 5th	Print	Retrospective cohort	US	4,536	958	3578	NA
Killerby, et al.	March 1st–April 7th	Print	Report	US	531	220	311	NA
Marcello, et al.	March 5th–April 9th	Print	Retrospective cohort	US	13,442	6,248	7194	52.7 [39.5–64.5]
McPadden, et al.	March 1st–April 30th	Pre‐print	Retrospective cohort	US	7,995	2,154	5841	NR
Mendy, et al.	March 13th–May 31st	Print	Retrospective cohort	US	689	216	473	44.4 [1.2]
Menezes Soares, et al.	February 29th–June 11th	Print	Cross‐sectional	Brazil	10,713	1,152	9561	NR
Mikami, et al.	March 13th–April 17th	Print	Retrospective cohort	US	6,493	3,708	2785	59.0 [43.0–72.0]
Miller, et al.	March 7th–April 30th	Print	Retrospective cohort	US	3,633	2,316	1317	58.4 [18.1]
Nouchi, et al.	March 23rd–March 27th	Print	Cross‐sectional	France	390	198	192	NA
Ortiz‐Brizuela, et al.	February 26th–March 23rd	Print	Prospective cohort	Mexico	309	140	169	43.0 [33.0–54.0]
Petrilli, et al.	March 1st–May 5th	Print	Prospective cohort	US	5,279	2,741	2538	54.0 [38.0–66.0]
Reilev, et al.	February 27th–May 19th	Print	Retrospective cohort	Denmark	11,122	2,254	8868	48.0 [33.0–62.0]
Rentsch, et al.	February 8th–March 30th	Pre‐print	Retrospective cohort	US	585	297	288	66.1 [60.4–71.0]
Shah, et al.	March 20th–April 22nd	Print	Prospective cohort	US	77	22	55	44.0 [19.0]
Singer, et al.	March 12th–April 14th	Print	Retrospective cohort	US	1,651	737	914	50.0 [18.0]
Suleyman, et al.	March 9th–March 27th	Print	Case series	US	463	355	108	57.5 [16.8]
Tenforde, et al.	April 15th–May 24th	Print	Report	US	350	79	271	43.0 [32.0–57.0]
Thompson, et al.	February 29th–June 1st	Print	Report	US	203,792	54,211	149,581	NR
Van Gerwen, et al.	March–May	Print	Retrospective cohort	US	3,703	2,015	1688	56.8 [18.2]
Vial, et al.	March 3rd–April 4th	Print	Cross‐sectional	Chile	381	88	293	NA
Yan, et al.	March 3rd–April 8th	Print	Retrospective cohort	US	128	26	102	NA
Zhang, X., et al.	March 16th–June 29th	Print	Prospective cohort	UK	1,596	1,020	576	68.8 [9.2]
Zuniga‐Moya, et al.	March 17th–May 4th	Print	Retrospective cohort	Honduras	877	220	657	NR

Note: NA: the data was not available the total sample, but reported stratified by group (hospitalised, Intensive Care Unit (ICU), outpatient); NR: not reported means or medians. Data was collected in categories.