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. 2021 Nov 30;17:3459–3470. doi: 10.2147/NDT.S339090

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© 2021 Borentain et al.

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Least Square Mean Change (SE) in Montgomery–Åsberg Depression Rating Scale Item 4 Score Over Time in the Double-Blind Treatment Phase.

Notes: *P ≤ 0.02, ^†P ≤ 0.001; LS mean difference between groups from ANCOVA model with fixed effects for treatment, region, class of oral antidepressant (SNRI or SSRI), study ID and baseline value as a covariate. Analysis is based on change from baseline.

Abbreviations: LS, least squares; MADRS, Montgomery–Åsberg Depression Rating Scale; SE, standard error.