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. 2021 Dec 3;7(3):e002019. doi: 10.1136/rmdopen-2021-002019

Table 1.

Characteristics of patients with SLE receiving booster vaccine

Patient Age Sex Duration of SLE* (years) Immunosuppressive treatments Initial vaccine series Booster vaccine type Days from initial to booster vaccine Anti-RBD pan-Ig¶ by Roche Elecys (U/mL) Anti-RBD-IgG¶ by Abbott assay (AU/mL) sVNT‡ (% inhibition) IFN-γ ELISpot§
(SFC/106 PBMCs)
Prebooster Postbooster† Prebooster Postbooster† Prebooster (%) Postbooster (%)† Postbooster†
1 27 Female 5 Azathioprine 100 mg/day
Ciclosporin 100 mg/day
Prednisolone 10 mg/day
CoronaVac Pfizer 113 342 24 416 275 36 182 16.74 99.70 62
2 19 Female 0 Prednisolone 10 mg/day
Hydroxychloroquine 1000 mg/week
CoronaVac Pfizer 94 83 15 076 332 25 719 27.94 98.98 228
3 50 Female 24 Mycophenolate mofetil 1000 mg/day
Prednisolone 10 mg/day
Hydroxychloroquine 400 mg/week
CoronaVac Pfizer 83 50 18 213 96 26 152 <1 99.42 88
4 50 Female 13 Prednisolone 5 mg/day
Hydroxychloroquine 1400 mg/week
CoronaVac ChAdOx1 86 21 6098 170 9756 4.79 99.19 414
5 41 Female 24 Prednisolone 5 mg/day
Hydroxychloroquine 1400 mg/week
CoronaVac Pfizer 92 32 21 759 104 34 784 <1 99.48 624
6 23 Female 17 Prednisolone 5 mg/day CoronaVac Pfizer 72 97 15 087 300 25 955 12.56 94.95 646
7 21 Female 4 Azathioprine 100 mg/week
Prednisolone 2.5 mg/day
Hydroxychloroquine 1000 mg/week
CoronaVac Pfizer 97 434 85 024 916 80 051 74.93 99.48 1200
8 29 Female 8 Tacrolimus 5 mg/day
Prednisolone 2.5 mg/day
Hydroxychloroquine 400 mg/week
CoronaVac Pfizer 92 NA 71 508 NA 96 572 NA 99.64 NA

*Systemic lupus erythematosus.

†14 days after booster vaccination.

‡SARS-CoV-2 Surrogate Virus Neutralization Test (NeutraLISA, Euroimmun, Lübeck, Germany) reported as % neutralisation.

§IFN-γ ELISpot reported as spot-forming cell per million peripheral blood mononuclear cells.

¶Anti-SARS-CoV-2 spike receptor binding domain (RBD) IgG antibody concentrations reported as.U/mL or AU/mL.

ELISpot, enzyme-linked immunosorbent spot; IFN-γ, interferon gamma; NA, not applicable; SFC, spot-forming cell; SLE, systemic lupus erythematosus.