Table 2.
Longitudinal sample characteristics.
| Total Sample N = 74 |
PiB− N = 47 |
PiB+ N = 27 |
|
|---|---|---|---|
| M, SD or % (N) | M, SD or % (N) | M, SD or % (N) | |
| Age, y | 85.34 ± 2.97 | V 85.28 ± 2.62 | 85.44 ± 3.56 |
|
| |||
| Sex (Female) | 43.2% (32) | 38.3% (18) | 51.9% (14) |
|
| |||
| Education, y | 14.99 ± 2.70 | 15.2 ± 2.78 | 14.56 ± 2.56 |
|
| |||
| ApoE ε4+ | 17.6% (13) | 8.5% (4) | 33.3% (9) |
|
| |||
| Heart Disease | 13.5% (10) | 14.9% (7) | 11.1% (3) |
|
| |||
| Diabetes | 4.1% (3) | 4.3% (2) | 3.7% (1) |
|
| |||
| Anti-hypertensive medication, % yes | 66.2% (49) | 66% (31) | 66.7% (18) |
|
| |||
| CES-D | 3.62 ± 4.27 | 2.96 ± 4.38 | 4.78 ± 3.9 |
|
| |||
| sCD14 | 1381.1 ± 277.59 | 1360.86 ± 298.6 | 1416.32 ± 237.79 |
|
| |||
| CRP | 1.83 ± 1.79 | 1.8 ± 1.56 | 1.97 ± 2.17 |
|
| |||
| sTNFr1 | 1278.34 ± 363.31 | 1317 ± 374.37 | 1211.06 ± 339.46 |
|
| |||
| sTNFr2 | 6231.58 ± 1623.94 | 6388.65 ± 1815. 94 | 5958.18 ± 1203.3 |
|
| |||
| IL-6 | 2.67 ± 1.74 | 2.70 ± 1.62 | 2.60 ± 1.96 |
|
| |||
| Duration blood draw to PET, weeks | 82.12 ± 28.10 | 84.78 ± 33.21 | 77.48 ± 14.19 |
|
| |||
| Duration, consecutive scans (weeks) | 96.59 ± 26.89 | 90.92 ± 23.12 | 106.48 ± 30.33 |
Abbreviations: APOE= apolipoprotein; sCD14 = soluble cluster of differentiation 14; CES-D = Center for Epidemiological Studies Depression; CRP = C-reactive protein; IL-6 = Interleukin-6; MMSE = Mini Mental Status Exam; sTNFr1 = soluble Tumor Necrosis Factor receptor; sTNFr2 = soluble Tumor Necrosis Factor receptor 2