Table 2.

Association between antibiotics and mortality (cancer-related mortality and all-cause mortality) by various statistical analyses

	aHR*	95% CI	p value
Cancer-related mortality
PS matching (n = 155, deaths = 96)	1.66	1.08–2.54	0.020
PS regression adjustment (n = 395, deaths = 231)	1.55	1.07–2.26	0.022
Multivariable analysis (n = 395, deaths = 231)	1.74	1.17–2.57	0.006
All-cause mortality
PS matching (n = 155, deaths = 121)	1.75	1.19–2.55	0.004
PS regression adjustment (n = 395, deaths = 286)	1.63	1.17–2.28	0.004
Multivariable analysis (n = 395, deaths = 286)	1.81	1.28–2.57	<0.001

aHR, adjusted hazard ratio; 95% CI, 95% confidence interval; PS, propensity score; PPIs, proton pump inhibitors; TACE, transarterial chemoembolization; DM, diabetes mellitus; IHD, ischemic heart disease; AF, atrial fibrillation; CHF, congestive heart failure; AFP, alpha fetoprotein; ALP, alkaline phosphatase; ALT, alanine aminotransferase; AST, aspartate aminotransferase; INR, international normalized ratio.

^*Adjusted for age of receiving immunotherapy, sex, type of immunotherapy, prior hepatectomy/TACE/ablative therapy, alcohol-related diseases, DM, hypertension, IHD, AF, CHF, stroke, hepatic decompensation, cause of cirrhosis, prednisolone, aspirin, statins, PPIs, prior sorafenib/lenvatinib use, AFP, bilirubin, ALP, ALT, AST, albumin, globulin, INR, platelet, creatinine, sodium.