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. 2021 Feb 11;45(7):1417–1424. doi: 10.1002/jpen.2060

Table 1.

Protein and Lactoferrin levels, pH, and Osmolality in Unfortified HM and HM Fortified with BMF and BCF

HM HM+BMF HM+BCF
Parameters Preterm (n = 5) Term (n = 5) Preterm (n = 5) Term (n = 5) Preterm (n = 5) Term (n = 5)
Protein, g/100 mL 1.6 ± 0.1 1.2 ± 0.03* 3.0 ± 0.1 2.6 ± 0.03 * 3.0 ± 0.1 2.6 ± 0.03*
1.4 ± 0.1a 2.8 ± 0.1b 2.8 ± 0.1b
Lactoferrin, mg/L 175 ± 24 115 ± 22 154 ± 30 105 ± 8 225 ± 34 183 ± 20
145 ± 18ab 130 ± 17a 204 ± 20b
pH 6.89 ± 0.09 6.91 ± 0.11 6.99 ± 0.07 6.96 ± 0.08 6.73 ± 0.07 6.76 ± 0.09
6.90 ± 0.07 ab 6.98 ± 0.05a 6.75 ± 0.05b
Osmolality, mOsm/kg H2O 307 ± 1.56 298 ± 0.74 * 415 ± 3.01 410 ± 3.25 342 ± 2.54 337 ± 2.97
303 ± 1.65a 412.50 ± 2.22b 339.40 ± 1.98c

Values are mean ± SD; groups in the same row not sharing the same letters are significantly different (P < .05).

BCF, bovine colostrum processed by mild thermal treatment as a fortifier; BMF, HM fortifier based on highly processed mature bovine milk; HM, human milk.

* P < .05, comparing preterm vs term milk samples, with or without fortification.