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. Author manuscript; available in PMC: 2022 Nov 20.
Published in final edited form as: Lancet. 2021 Nov 3;398(10314):1894–1904. doi: 10.1016/S0140-6736(21)01789-X

Table 2:

Common Treatment Regimens Received at Cycle One

Treatment regimen All patients (N=718) GA arm (N=349) Usual care arm (N=369)
Lung cancer regimens N=180 N=64 N= 116
Pemetrexed- carboplatin +/− pembrolizumab 66 (36%) 13 (20%) 53 (46%)
Paclitaxel- carboplatin +/− monoclonal antibody 36 (20%) 20 (30%) 16 (14%)
Carboplatin- etoposide 20 (10%) 5 (8%) 15 (13%)
Carboplatin- nab paclitaxel 17 (9%) 7 (11%) 10 (9%)
Gastro-intestinal cancers regimens N=246 N=132 N= 114
FOLFOX +/− bevacizumab 65 (26%) 25 (19%) 40 (35%)
Gemcitabine- nab paclitaxel 44 (18%) 24 (18%) 20 (18%)
Capecitabine 23 (9%) 21(16%) 2 (2%)
FOLFIRI +/− bevacizumab 18 (7%) 12 (9%) 6 (5%)
FOLFIRINOX +/− bevacizumab 9 (4%) 3 (2%) 6 (5%)
Genito-urinary cancers regimens N=109 N=56 N= 53
 Abiraterone +/− prednisone 35 (32%) 22 (39%) 13 (25%)
 Docetaxel +/− prednisone 32 (29%) 19 (34%) 13 (25%)
  Enzalutamide +/− prednisone 13 (12%) 3 (5%) 10 (19%)
 Gemcitabine carboplatin 11 (10%) 3 (5%) 8 (15%)
Breast Cancer regimens N= 56 N= 19 N= 37
Palbociclib+ AI 18 (32%) 6 (32%) 12 (32%)
Paclitaxel +/− trastuzumab 8 (14%) 1 (5%) 8 (22%)
Gemcitabine carboplatin +/− trastuzumab 5 (9%) 2 (11%) 3 (8%)
Capecitabine 4 (7%) 0 (0%) 4 (11%)
Lymphoma Regimens N=46 N=23 N= 23
BR 18 (39%) 7 (30%) 11(48%)
R-CHOP 9 (20%) 5 (22%) 4(17%)
Gynecological cancers regimens N=43 N=29 N= 14
Paclitaxel carboplatin 19 (44%) 10 (35%) 9 (60%)
*

This table only included commonly received regimens at cycle one

Abbreviations: AI, aromatase inhibitors; BR, bendamustine/rituximab; FOLOFOX, 5-fluorouracil/ leucovorin/ oxaliplatin; FOLFIRI, 5-fluorouracil/ leucovorin/ irinotecan; FOLFIRINOX/ 5-fluorouracil/ leucovorin/ oxaliplatin/ irinotecan; R-CHOP, rituximab/ cyclophosphamide/ doxorubicin/ prednisone/ vincristine