Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Nov 23;30:09636897211057465. doi: 10.1177/09636897211057465

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2021

This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).

PMC Copyright notice

Figure 6. — KEGG pathway enrichment analyses of target genes of miRNA in HucMSC-derived exosomes. (A) KEGG enrichment bubble map of target genes predicted by differentially expressed miRNA between osteogenic group 3 and control group. (B) Bubble map of target genes predicted by differentially expressed miRNA between osteogenic group 7 and control group. (C) KEGG enrichment analysis of target genes predicted by differentially expressed miRNA between osteogenic group 3 and 7. The X-axis is the enrichment ratio (the ratio of the number of genes annotated to an item in a selected gene set to the total number of genes annotated to that item by the species), and the Y-axis is KEGG Pathway; the size of the bubble represents the number of genes annotated to a KEGG Pathway. The color represents the enrichment P value. (D) KEGG enrichment result of target genes regulated by critical microRNAs in MSC-secreted exosomes during osteogenic induction. (E) TargetScan and miRBase databases were applied to analyze the target genes of hsa-mir-328-3p and hsa-mir-2110. Shown are complementary base pairing sequences of the miRNA 3´-UTR region.