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. 2021 Nov 24;49(11):03000605211058376. doi: 10.1177/03000605211058376

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© The Author(s) 2021

Creative Commons Non Commercial CC BY-NC: This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).

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Figure 2. — Chemerin regulated cell proliferation and apoptosis in vitro. (a and b) CMKLR1 protein levels were upregulated by transfection with LV5-chemerin and downregulated by transfection with LV3-590 and LV3-1623. (c) CMKLR1 mRNA levels were upregulated by transfection with LV5-chemerin and downregulated by transfection with LV3-590 and LV3-1623. (d) COV434 cell proliferation was detected using an EdU fluorescence microscope. (e) Apoptotic cells were measured by flow cytometry. Error bars represent standard error. Bars show mean ± standard deviation of three independent experiments. *P < 0.05, **P < 0.01, ***P < 0.001 compared with control group.